Craig Barr Taylor, M.D. Research
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Eating Disorders Prevention Studies
Eating Disorder Risk factor Studies. McKnight Longitudinal Risk Factor Study: In collaboration with investigators at the University of Arizona, Tucson, we have been following cohorts of adolescents, first evaluated in 4-9th grades and then reevaluated yearly thereafter for up to three years. The major goals of this project are: (1) to assess risk factors for the development of excessive weight concerns, (2) to assess risk factors that protect against the development of excessive weight concerns and eating disorders, (3) to assess risk factors that promote the development of eating disorders, and (4) to assess how these risk and protective factors change over time. The combined sample includes a large number of African-American, Hispanic and Asian public school students. This study will provide important information on risk factors for the onset of clinical eating disorders.
We are also following a cohort of young women in an all-girls private school to provide companion data to the above study on a more economically advantaged population.
Collaboration with Channing Laboratory. We collaborate with Alison Field, ScD, of the Harvard Channing Laboratory to evaluate risk factors in her large (n = 10,000) sample of young men and women followed longitudinally.
Prevention Dissemination studies. Following completion of the McKnight Risk Factor study, we plan to begin dissemination of a brief screening instrument to identify middle and high school students at high risk of developing an eating disorder.
Intervention to reduce the incidence of eating disorders. We have begun a large, NIMH-sponsored, multisite, long-term study to determine if reduction in eating disorder risk factors in students likely to develop eating disorders will reduce the incidence of eating disorders. School-based risk reduction. We have developed and are now evaluating a multimedia intervention (Student Bodies) to reduce weight/shape concerns in 9 and 10th grade adolescents in a local private school.
School-based risk reduction. We have developed and are now evaluating a multimedia intervention (Student Bodies) to reduce weight/shape concerns in 9 and 10th grade adolescents in a local private school.
Other studies include work on population based interventions, the use of on-line groups to provide psychoeducation programs and treatment to subclinical/clinical eating disorders and risk factor/intervention studies in Japan, Switzerland and France.
Cardiac Rehabilitation/Chronic Disease Management
Depression and Heart Disease. Dr. Taylor is Co-PI on the Stanford site of the NHLBI study: Enhancing Recovery in Coronary Heart Disease (ENRICHD) Patients study. The major goals of this project are to develop potentially cost-effective interventions that can be widely disseminated and to integrate interventions for coronary risk factor modification, social isolation and depression into the usual care provided to patients following acute myocardial infarction. Approximately 300 post-MI patients have been randomized into an individual cognitive behavioral program followed by group treatment to reduce depression and/or social isolation. Results of this multisite national trial will be available in late 2001.
Management of Chronic Disease. The purpose of this study, funded by the Robert Wood Johnson Foundation, is to develop and evaluate a chronic disease management system, with an initial focus on patients with diabetes, CVD and CVD risk factors. Approximately 170 patients with diabetes have been randomized to the intervention or usual care and followed for a year. The model combines nurse care management, algorithms, evidence-based medicine and outcomes, group therapy in a comprehensive treatment model.
Breast cancer: The Development and Evaluation of an Innovative Internet-Based Breast Cancer Psychosocial Intervention (Bosom Buddies). This project is evaluating the effects of a structured, 12-week, Internet-based psychosocial intervention for breast cancer patients. We are also developing programs to assist in process analyses of the group and to reduce facilitator time.
Other projects focused on other chronic care disease models both here and in other countries, the interaction of maltreatment and utilization (see Bruce Arnow, Ph.D.) and the development of psychosocial interventions for primary-care.
Also see: Bob DeBusk, M.D.
Anxiety Studies.
Physiology studies. Dr. Taylor works with Dr. Walton T. Roth and his colleagues to study, with ambulatory physiological monitoring, differences between anxiety disorders such as Panic Disorder, with and without Agoraphobia, and Generalized Anxiety Disorder.
Computer-assisted therapy studies. Dr. Taylor, with Justin Kenardy at the University of Queensland in Brisbane, Mike Dow and Derek Johnston at St. Andrews University and Michelle Newman at Penn State, have recently completed an international study examining the benefits of computer-assisted therapy for panic disorders. This group will continue cutting edge studies to provide computer assisted/cost-effective treatments for anxiety disorders.
Also see Walton T. Roth, M.D.
Population-based Research.
Dissemination of a Smoking Cessation Program for Inpatients. The goal of this project, funded by the Tobacco-Related Disease Research Program (Prop. 99), is to evaluate issues related to disseminating a scientifically-tested smoking cessation program for inpatients to a wide range of hospitals in Santa Clara County. The program involves 8 hospitals in the South Peninsula. We are also developing a web-based health care provider training program.
Neighborhood-Level Influences on All-Cause Mortality. Dr. Taylor collaborates with Marilyn Winkleby (PI) on a follow-up study to the Stanford Five City Project. This study will test the independent and interrelated effects of the neighborhood social environment (e.g., neighborhood SES, social disorganization, Hispanic concentration, crime rates), neighborhood physical environment (e.g., housing conditions, availability of goods and services such as licensed alcohol distributors, fast food restaurants, grocery stores; educational resources, recreational facilities; banking/lending institutions), and individual risk factors in predicting all-cause and CVD mortality in women and men
Smoking Cessation - TRDRP
